Recommended positive controls: HepG2.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (93%), Xenopus laevis (92%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
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Protein Aliases: heterotaxy 1; ZIC; Zic family member 3 (odd-paired homolog, Drosophila); ZIC1; ZIC2; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; Zinc finger protein ZIC 3; ZNF201
Gene Aliases: HTX; HTX1; RGD1561261; VACTERLX; ZIC3; ZNF203
UniProt ID: (Human) O60481