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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ZIP14 Antibodies

          Invitrogen

          ZIP14 Polyclonal Antibody

          5 Published Figures
          8 References
          View all (11) ZIP14 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite ZIP14 Polyclonal Antibody

          • Published Figures (5)
          ZIP14 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ZIP14 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          ZIP14 Antibody (PA5-21077) in ICC/IF

          Current issues in molecular biology 2022 - Immunofluorescence detection of ZIP14 transporter in normozoospermic ( a ) and asthenozoospermic ( c ) sperm samples using a confocal laser scanning microscope. Nc--negative control. Scale bar = 10 um. Average of total number of spermatozoa per ejaculate before processing was in normo- (625 x 10 6 /vol) and asthenozoospermia (367.5 x 10 6 /vol); For each type of sample, six randomly selected field areas wer... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ZIP14 Antibody in Immunocytochemistry (ICC/IF)
          ZIP14 Antibody in Immunohistochemistry (IHC)
          ZIP14 Antibody in Western Blot (WB)
          ZIP14 Antibody in Western Blot (WB)
          ZIP14 Antibody in Western Blot (WB)

          Product Details

          PA5-21077

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-4 µg/mL
          View 4 publications 4 publications

          Immunohistochemistry (IHC)

          -
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1-2 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A peptide corresponding to 16 amino acid synthetic peptide near the center of human ZIP14. The immunogen is located within amino acids 230-280 of ZIP14.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11157266

          Product Specific Information

          Suggested positive controls are human liver, mouse kidney, or rat kidney tissue lysates.

          PA5-21077 can be used with blocking peptide PEP-1191.

          Predicted species reactivity based on immunogen sequence: Bovine: (94%).

          At least three isoforms of ZIP14 are known to exist; this antibody will detect all isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.

          Target Information

          The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Factor for adipocyte differentiation 123; FAD-123; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; Metal cation symporter ZIP14; solute carrier family 39 (metal ion transporter), member 14; solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; zinc transporter ZIP14; ZIP-14; Zrt- and Cig19; Zrt- and Irt-like protein 14; Zrt-, Irt-like protein 14

          View more View less

          Gene Aliases: cig19; FAD-123; Fad123; HMNDYT2; KIAA0062; LZT-Hs4; NET34; SLC39A14; ZIP-14; ZIP14

          View more View less

          UniProt ID: (Human) Q15043, (Mouse) Q75N73

          View more View less

          Entrez Gene ID: (Human) 23516, (Rat) 306009, (Mouse) 213053

          View more View less

          Function(s)
          zinc ion transmembrane transporter activity ferrous iron transmembrane transporter activity metal ion transmembrane transporter activity secondary carrier transporter
          Process(es)
          cellular zinc ion homeostasis zinc II ion transmembrane transport zinc II ion transmembrane import ferrous iron transmembrane transport iron ion transport zinc II ion transport ferrous iron transport iron ion transmembrane transport transport ion transport metal ion transport transmembrane transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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