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ZIP5 Polyclonal Antibody
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Product Details
600-401-GF0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-ZIP5 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the internal region of human ZIP5.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC34778; solute carrier family 39 (metal ion transporter), member 5; solute carrier family 39 (zinc transporter), member 5; Solute carrier family 39 member 5; unnamed protein product; zinc transporter 5; Zinc transporter ZIP5; ZIP-5; Zrt- and Irt-like protein 5; ZRT/IRT-like protein 5
Gene Aliases: 1810013D05Rik; 2010205A06Rik; LZT-Hs7; MYP24; SLC39A5; ZIP5
UniProt ID: (Human) Q6ZMH5, (Mouse) Q9D856
Entrez Gene ID: (Human) 283375, (Mouse) 72002
eye development
ion transport
zinc II ion transport
bicarbonate transport
metal ion transport
cellular cation homeostasis
BMP signaling pathway
cellular response to zinc ion starvation
positive regulation of mRNA splicing, via spliceosome
transmembrane transport
neural precursor cell proliferation
G1 to G0 transition involved in cell differentiation
zinc II ion transmembrane transport
zinc II ion transmembrane import
transport
cellular zinc ion homeostasis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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