This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
It is not recommended to aliquot this antibody.
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
Protein Aliases: DAP kinase 3; DAP-like kinase; DAP3K; death-associated kinase 3; Death-associated like kinase; Death-associated protein kinase 3; Dlk; MYPT1 kinase; ZIP kinase; ZIP kinase isoform; ZIP-kinase; Zipper-interacting protein kinase
Gene Aliases: DAPK3; Dapkl; DLK; ZIP; ZIPK
Molecular Function: non-receptor serine/threonine protein kinase