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Product Details
PA5-59263
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZMIZ2. Recombinant protein control fragment (Product #RP-89718).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2649937
Product Specific Information
Immunogen sequence: LMPSVMEMIA ALGPGAAPFA PLQPPSVPAP SDYPGQGSSF LGPGTFPESF PPTTPSTPTL AEFTPGPPPI SYQSDIPSSL LTSEKSTACL PSQMAPAGHL DPTHNPGTPG LHTSNL
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 85%.
Target Information
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PIAS-like protein Zimp7; Zinc finger MIZ domain-containing protein 2; zinc finger, MIZ-type containing 2
Gene Aliases: HRIHFB2007; hZIMP7; KIAA1886; NET27; TRAFIP20; ZIMP7; ZMIZ2
UniProt ID: (Human) Q8NF64
Entrez Gene ID: (Human) 83637
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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