|Tested species reactivity||Human, Mouse, Zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide between amino acids 1-100 of the human ZMPSTE24 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris glycine with 150mM NaCl|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1.0-2.0 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: human and mouse testis protein or cell lysate.
ZMPSTE24 is a zinc metalloprotease involved in the post-translational processing of LMNA precursors. Mutations in ZMPSTE24 have been associated with human diseases, often due to the accumulation of LMNA precursors. It is possible that ZMPSTE24, due to its association with LMNA, plays some role in human ageing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.