This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked cognitive disability. Several alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: DXHXS6673E protein; Zinc finger MYM-type protein 3; Zinc finger protein 261; zinc finger, MYM-type 3
Gene Aliases: 9030216B10Rik; AW122925; DXS6673E; DXS6673El; KIAA0385; MYM; XFIM; Zfp261; ZMYM3; ZNF198L2; ZNF261