PA5-34417 can be used with blocking peptide PEP-1459.
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
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Protein Aliases: cell death inhibiting RNA; MYM type 4; Zinc finger MYM-type protein 4; Zinc finger protein 262; zinc finger, MYM-type 4
Gene Aliases: CDIR; KIAA0425; MYM; ZMYM4; ZNF198L3; ZNF262
UniProt ID: (Human) Q5VZL5
Entrez Gene ID: (Human) 9202