Immunogen sequence: QNQIQPMSHS AFFNKKTLNT ESNCEYKDPG KMIRTRPHLA SSQKQPQKCC LFTESLKLNL EVNGQNESND TEQLDDVVGS GQLFSHSSSD ACSKNIHTGE TFCKGNQCRK VCGHKQSLKQ HQ
Highest antigen sequence identity to the following orthologs: Mouse - 39%, Rat - 42%.
ZNF175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. As a transcriptional suppressor, this protein plays a role in macrophage control of viral replication during advanced HIV-1 infection.
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Protein Aliases: Zinc finger protein 175; Zinc finger protein OTK18
Gene Aliases: OTK18; ZNF175
UniProt ID: (Human) Q9Y473
Entrez Gene ID: (Human) 7728