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ZNF238 is the sequence-specific DNA-binding protein with transcriptional repression activity. ZNF238 binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. ZNF238 may play a role in the organization of chromosomes in the nucleus.C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.
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Protein Aliases: 58 kDa repressor protein; rRP58; TAZ-1; Transcriptional repressor RP58; Translin-associated zinc finger protein 1; Zfp-238; Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238; Zinc finger protein C2H2-171
Gene Aliases: C2H2-171; MRD22; RP58; TAZ-1; TAZ1; ZBTB18; Zfp238; ZNF238
UniProt ID: (Human) Q99592, (Mouse) Q9WUK6, (Rat) Q9JKY3
Entrez Gene ID: (Human) 10472, (Mouse) 30928, (Rat) 64619
Molecular Function:
DNA binding protein
centromere DNA-binding protein
nucleic acid binding
transcription factor
zinc finger transcription factor
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