Peptide sequence: YDIVKVCKKK LKEKATTEAD STKKEEDASS CSDKVESLSD GSSHIAGDLP
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
ZNF238 is the sequence-specific DNA-binding protein with transcriptional repression activity. ZNF238 binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. ZNF238 may play a role in the organization of chromosomes in the nucleus.C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.
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Protein Aliases: 58 kDa repressor protein; TAZ-1; Transcriptional repressor RP58; Translin-associated zinc finger protein 1; Zinc finger and BTB domain-containing protein 18; Zinc finger protein 238; Zinc finger protein C2H2-171
Gene Aliases: C2H2-171; MRD22; RP58; TAZ-1; TAZ1; ZBTB18; ZNF238
UniProt ID: (Human) Q99592
Entrez Gene ID: (Human) 10472