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Immunogen sequence: MSAQSVEED SILIIPTPDE EEKILRVKLE EDPDGEEGSS IPWNHLPDPE IFRQRFRQFG YQDSPGPREA VSQLRELCRL WLRPETHTKE QILELVVLEQ FVAILPKELQ TWVRDHHPEN GEEAVTVLED LESELDDPGQ PVSLRRRKRE VLVEDMVSQE EAQGLPSSEL DAVENQLKWA SWELHSLRHC DDDGRTENGA LAPKQELPSA LESHEVPGTL SMGVPQIFKY GETCFPKGRF ERKRNPSRKK QHICDECGKH FSQGSALILH QRIHSGEKPY GCVECGKAFS RSSILVQHQR VHTGEKPYKC LECGKAFSQN SGLINHQRIH TGEKPYECVQ CGKSYSQSSN LFRHQRRHNA EKLLNVVKV (1-368 aa encoded by BC016801 )
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hypomyelinated CNS protein; Retinoic acid suppression protein A; RSG-A; Zfp-191; Zinc finger and SCAN domain-containing protein 3; Zinc finger protein 191; Zinc finger protein 24; zinc finger protein 24 (KOX 17); Zinc finger protein KOX17; Zinc finger protein ZF-12; zinc finger ZF-12
Gene Aliases: 3526401F17Rik; 5033419P20Rik; AI480505; AI642085; AL024422; Hmcns; KOX17; RSG-A; ZF-12; Zfp191; Zfp24; ZNF191; ZNF24; Znp191; ZSCAN3
UniProt ID: (Human) P17028, (Mouse) Q91VN1, (Rat) Q7TNK3
Entrez Gene ID: (Human) 7572, (Mouse) 59057, (Rat) 360204
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