Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: HFRQYPAHVS QPANHVTSMA KAIMPVSLSE GRSTDSPVTM KSSSEPGYKM SSPQVVSPNY SDSLPPGTQC LVGAMVSGGG RNESSPDSKR LSTSDINSRD SKRVKLRDGI PGVPSLAVVP SDMSSTISTN TPSQGICNSS NHVQNGVTFP WPDANGKA
Highest antigen sequence identity to the following orthologs: Mouse - 35%, Rat - 35%.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. SUHW1 (Suppressor of hairy wing homolog 1), also known as ZNF280A (Zinc finger protein 280A), 3'OY11.1, ZNF636 or ZNF280, is a 542 amino acid protein that contains four C2H2-type zinc fingers. Localized to the nucleus, SUHW1 is thought to function as a transcription factor that may mediate transcriptional regulation events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'OY11.1; Suppressor of hairy wing homolog 1; zinc finger protein 280; Zinc finger protein 280A; Zinc finger protein 636
Gene Aliases: 3'OY11.1; SUHW1; ZNF280; ZNF280A; ZNF636
UniProt ID: (Human) P59817
Entrez Gene ID: (Human) 129025
Molecular Function: C2H2 zinc finger transcription factor
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