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Product Details
PA5-53660
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ZNF408
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2650107
Product Specific Information
Immunogen sequence: AAVAVVTEVE SAVQQEVASP GEDAAEPCID PGSQSPSGIQ AENMVSPGLK FPTQDRISKD SQPLGPLLQD GDVDEECPAQ AQMPPELQSN SATQQDPDGS GASFSSSARG TQPHGYLAKK LHSPSDQCPP RAKTPEPGAQ QSGFPTLSRS
Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 25%.
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kruppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains 10 C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PR domain zinc finger protein 17; Zinc finger protein 408
Gene Aliases: EVR6; PFM14; PRDM17; RP72; ZNF408
UniProt ID: (Human) Q9H9D4
Entrez Gene ID: (Human) 79797
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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