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Invitrogen
ZNF50 Polyclonal Antibody
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FIGURE: 1 / 3
ZNF50 Antibody (PA5-37087) in IHC (P)
Immunohistochemistry analysis of ZNF50 in paraffin-embedded human stomach carcinoma tissue (nucleus staining) and negative control (right, with PBS only). Samples were incubated with ZNF50 polyclonal antibody (Product # PA5-37087) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Product Details
PA5-37087
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 363-408 of human ZNF50
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 55 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZSCAN22 (zinc finger and SCAN domain-containing protein 22), also known as HKR2 or ZNF50 (zinc finger protein 50), is a 491 amino acid nuclear protein. Belonging to the Krueppel C2 H2-type zinc-finger protein family, ZSCAN22 contains eight C2 H2-type zinc fingers and one SCAN box domain. ZSCAN22 may be involved in transcriptional regulation, and becomes phosphorylated upon DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GLI-Kruppel family member HKR2; Krueppel-related zinc finger protein 2; Protein HKR2; Zinc finger and SCAN domain-containing protein 22; Zinc finger protein 50; zinc finger protein 8-like
Gene Aliases: AW227621; D530006B18Rik; HKR2; ZNF50; ZSCAN22
UniProt ID: (Human) P10073
Entrez Gene ID: (Rat) 102553002, (Human) 342945, (Mouse) 232878
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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