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alpha Tubulin Polyclonal Antibody

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alpha Tubulin Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( -20°C Ethanol ) fixed HepG2 cells using 11224-1-AP (alpha Tubulin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

alpha Tubulin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human endometrial cancer using 11224-1-AP (alpha Tubulin antibody) at dilution of 1:50 (under 40x lens).

alpha Tubulin Antibody in Western Blot (WB) — Mouse uterus tissue were subjected to SDS PAGE followed by western blot with 11224-1-AP (alpha Tubulin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

alpha Tubulin Antibody in Flow Cytometry (Flow) — 1X10^6 HEK-293 cells were stained with 0.2ug alpha Tubulin antibody (11224-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). FITC-Goat anti-Rabbit IGG with dilution 1:100.

alpha Tubulin Antibody in Immunoprecipitation (IP) — IP result of anti-alpha Tubulin (IP:11224-1-AP, 3ug; Detection:11224-1-AP 1:1000) with HeLa cells lysate 5000ug.

Product Details

11224-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:800-1:8000	View 130 publications 130 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	View 11 publications 11 publications
Flow Cytometry (Flow)	0.2 µg/1x10^6 cells	-
Immunoprecipitation (IP)	0.5-4.0 µg	-
Miscellaneous PubMed (Misc)	-	View 34 publications 34 publications

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat, Zebrafish
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	alpha Tubulin Fusion Protein Ag1727 (1-451 aa encoded by BC009314)
Conjugate	Unconjugated
Form	Liquid
Concentration	0.29 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.1% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MRECISIHV GQAGVQIGNA CWELYCLEHG IQPDGQMPSD KTIGGGDDSF NTFFSETGAG KHVPRAVFVD LEPTVIDEVR TGTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIIDLVL DRIRKLADQC TGLQGFLVFH SFGGGTGSGF TSLLMERLSV DYGKKSKLEF SIYPAPQVST AVVEPYNSIL TTHTTLEHSD CAFMVDNEAI YDICRRNLDI ERPTYTNLNR LISQIVSSIT ASLRFDGALN VDLTEFQTNL VPYPRIHFPL ATYAPVISAE KAYHEQLSVA EITNACFEPA NQMVKCDPRH GKYMACCLLY RGDVVPKDVN AAIATIKTKR SIQFVDWCPT GFKVGINYQP PTVVPGGDLA KVQRAVCMLS NTTAIAEAWA RLDHKFDLMY AKRAFVHWYV GEGMEEGEFS EAREDMAALE KDYEEVGVDS VEGEGEEEGE EY (1-451 aa encoded by BC009314)

Target Information

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Lv G,Zhu H,Li C,Wang J,Zhao D,Li S,Ma L,Sun G,Li F,Zhao Y,Gao Y

Fri Oct 20 00:00:00 EDT 2017

Regulation of m⁶A Transcripts by the 3'→5' RNA Helicase YTHDC2 Is Essential for a Successful Meiotic Program in the Mammalian Germline.

Molecular cell

Wojtas MN,Pandey RR,Mendel M,Homolka D,Sachidanandam R,Pillai RS

Thu Oct 19 00:00:00 EDT 2017

Neuroprotective Effects of Lycium barbarum Polysaccharide on Focal Cerebral Ischemic Injury in Mice.

Neurochemical research

Zhao P,Zhou R,Zhu XY,Liu G,Zhao YP,Ma PS,Wu W,Niu Y,Sun T,Li YX,Yu JQ,Qian ZM

Sun Oct 01 00:00:00 EDT 2017

HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress.

Biochimica et biophysica acta. Gene regulatory mechanisms

Fan Z,Li Z,Yang Y,Liu S,Guo J,Xu Y

Sun Oct 01 00:00:00 EDT 2017

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O⁶-methylguanine-DNA methyltransferase.

Redox biology

Chang KY,Hsu TI,Hsu CC,Tsai SY,Liu JJ,Chou SW,Liu MS,Liou JP,Ko CY,Chen KY,Hung JJ,Chang WC,Chuang CK,Kao TJ,Chuang JY

Sun Oct 01 00:00:00 EDT 2017

NOR1 Suppresses Cancer Stem-Like Cells Properties of Tumor Cells via the Inhibition of the AKT-GSK-3β-Wnt/β-catenin-ALDH1A1 Signal Circuit.

Journal of cellular physiology

Wang W,Yi M,Chen S,Li J,Zhang H,Xiong W,Li G,Li X,Xiang B

Sun Oct 01 00:00:00 EDT 2017

HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.

Neuroscience

Shi X,Li M,Huang K,Zhou S,Hu Y,Pan S,Gu Y

Sat Sep 30 00:00:00 EDT 2017

HMGB1 binding heptamer peptide improves survival and ameliorates brain injury in rats after cardiac arrest and cardiopulmonary resuscitation.

Neuroscience

Shi X,Li M,Huang K,Zhou S,Hu Y,Pan S,Gu Y

Sat Sep 30 00:00:00 EDT 2017

FAM83D, a microtubule-associated protein, promotes tumor growth and progression of human gastric cancer.

Oncotarget

Huang M,Ma X,Shi H,Hu L,Fan Z,Pang L,Zhu F,Yang X,Xu W,Liu B,Zhu Z,Li C

Tue Sep 26 00:00:00 EDT 2017

2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G₂/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells.

Oncotarget

Li X,Jiang Z,Feng J,Zhang X,Wu J,Chen W

Fri Sep 22 00:00:00 EDT 2017

Oncotarget

Li X,Jiang Z,Feng J,Zhang X,Wu J,Chen W

Fri Sep 22 00:00:00 EDT 2017

Palladin is a novel microtubule-associated protein responsible for spindle orientation.

Scientific reports

Zhang X,Chen X,Liu J,Xu X,Zhang Y,Ruan Z,Xie Y,Huang Q,Yin T,Chen Z,Chen S

Mon Sep 18 00:00:00 EDT 2017

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.

Nucleic acids research

Sun Y,Bao Y,Han W,Song F,Shen X,Zhao J,Zuo J,Saffen D,Chen W,Wang Z,You X,Wang Y

Mon Aug 21 00:00:00 EDT 2017

MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5.

Cell death & disease

Du B,Dai XM,Li S,Qi GL,Cao GX,Zhong Y,Yin PD,Yang XS

Thu Aug 10 00:00:00 EDT 2017

Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Chemico-biological interactions

Chen L,Chen DQ,Wang M,Liu D,Chen H,Dou F,Vaziri ND,Zhao YY

Tue Aug 01 00:00:00 EDT 2017

Anthocyanins from Black Chokeberry (Aroniamelanocarpa Elliot) Delayed Aging-Related Degenerative Changes of Brain.

Journal of agricultural and food chemistry

Wei J,Zhang G,Zhang X,Xu D,Gao J,Fan J,Zhou Z

Wed Jul 26 00:00:00 EDT 2017

BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.

The Journal of cell biology

Zhang X,Jiang S,Mitok KA,Li L,Attie AD,Martin TFJ

Mon Jul 03 00:00:00 EDT 2017

Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening.

Oncology reports

Zhou S,Xiao Y,Zhuang Y,Liu Y,Zhao H,Yang H,Xie C,Zhou F,Zhou Y

Sat Jul 01 00:00:00 EDT 2017

Motile hepatocellular carcinoma cells preferentially secret sugar metabolism regulatory proteins via exosomes.

Proteomics

Zhang J,Lu S,Zhou Y,Meng K,Chen Z,Cui Y,Shi Y,Wang T,He QY

Sat Jul 01 00:00:00 EDT 2017

Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Huijuan W,Xiaoxu C,Rui S,Xinghui L,Beibei T,Jianchun M

Sat Jul 01 00:00:00 EDT 2017

Long-Term Dietary Supplementation with Selenium-Enriched Yeast Improves Cognitive Impairment, Reverses Synaptic Deficits, and Mitigates Tau Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease.

Journal of agricultural and food chemistry

Zhang ZH,Wen L,Wu QY,Chen C,Zheng R,Liu Q,Ni JZ,Song GL

Wed Jun 21 00:00:00 EDT 2017

Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming.

Cell death & disease

Sun S,Liu J,Zhao M,Han Y,Chen P,Mo Q,Wang B,Chen G,Fang Y,Tian Y,Zhou J,Ma D,Gao Q,Wu P

Thu Jun 08 00:00:00 EDT 2017

Long noncoding RNA CRNDE stabilized by hnRNPUL2 accelerates cell proliferation and migration in colorectal carcinoma via activating Ras/MAPK signaling pathways.

Cell death & disease

Jiang H,Wang Y,Ai M,Wang H,Duan Z,Wang H,Zhao L,Yu J,Ding Y,Wang S

Thu Jun 08 00:00:00 EDT 2017

JOSD1 Negatively Regulates Type-I Interferon Antiviral Activity by Deubiquitinating and Stabilizing SOCS1.

Viral immunology

Wang X,Zhang L,Zhang Y,Zhao P,Qian L,Yuan Y,Liu J,Cheng Q,Xu W,Zuo Y,Guo T,Yu Z,Zheng H

Thu Jun 01 00:00:00 EDT 2017

Overexpression of WDFY2 inhibits prostate cancer cell growth and migration via inactivation of Akt pathway.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Wang J,Chen X,Tong S,Zhou H,Sun J,Gou Y,Wu F,Hu J,Xu J,Ding G

Thu Jun 01 00:00:00 EDT 2017

Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.

Virchows Archiv : an international journal of pathology

Zhang X,Fu L,Xue D,Zhang X,Hao F,Xie L,He J,Gai J,Liu Y,Xu H,Li Q,Wang E

Mon May 01 00:00:00 EDT 2017

Vav1 expression is increased in esophageal squamous cell carcinoma and indicates poor prognosis.

Biochemical and biophysical research communications

Zhu X,Jin H,Xia Z,Wu X,Yang M,Zhang H,Shang X,Cheng R,Zhan Z,Yu Z

Sat Apr 29 00:00:00 EDT 2017

Atorvastatin prevents Angiotensin II induced myocardial hypertrophy in vitro via CCAAT/enhancer-binding protein β.

Biochemical and biophysical research communications

Chen Y,Yu S,Zhang N,Li Y,Chen S,Chang Y,Sun G,Sun Y

Sat Apr 29 00:00:00 EDT 2017

Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.

Molecular neurobiology

Li Y,You QL,Zhang SR,Huang WY,Zou WJ,Jie W,Li SJ,Liu JH,Lv CY,Cong J,Hu YY,Gao TM,Li JM

Tue Apr 18 00:00:00 EDT 2017

Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines.

Acta biochimica Polonica

Bronowicka-Adamska P,Bentke A,Wróbel M

Mon Apr 17 00:00:00 EDT 2017

Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.

Oncotarget

Wang Y,Chu Y,Yue B,Ma X,Zhang G,Xiang H,Liu Y,Wang T,Wu X,Chen B

Tue Apr 04 00:00:00 EDT 2017

MiR-466b-1-3p regulates P-glycoprotein expression in rat cerebral microvascular endothelial cells.

Neuroscience letters

Yang X,Ren W,Shao Y,Chen Y

Mon Apr 03 00:00:00 EDT 2017

Non-hemolytic enterotoxin of Bacillus cereus induces apoptosis in Vero cells.

Cellular microbiology

Liu X,Ding S,Shi P,Dietrich R,Märtlbauer E,Zhu K

Sat Apr 01 00:00:00 EDT 2017

PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction.

Scientific reports

Qiao X,Jia S,Ye J,Fang X,Zhang C,Cao Y,Xu C,Zhao L,Zhu Y,Wang L,Zheng M

Mon Mar 27 00:00:00 EDT 2017

Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.

The EMBO journal

Dalet A,Argüello RJ,Combes A,Spinelli L,Jaeger S,Fallet M,Vu Manh TP,Mendes A,Perego J,Reverendo M,Camosseto V,Dalod M,Weil T,Santos MA,Gatti E,Pierre P

Wed Mar 15 00:00:00 EDT 2017

MicroRNA let-7g possesses a therapeutic potential for peripheral artery disease.

Journal of cellular and molecular medicine

Hsu PY,Hsi E,Wang TM,Lin RT,Liao YC,Juo SH

Wed Mar 01 00:00:00 EST 2017

A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity.

Nature communications

Xu X,Fan Z,Liang C,Li L,Wang L,Liang Y,Wu J,Chang S,Yan Z,Lv Z,Fu J,Liu Y,Jin S,Wang T,Hong T,Dong Y,Ding L,Cheng L,Liu R,Fu S,Jiao S,Ye Q

Tue Jan 17 00:00:00 EST 2017

Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.

Scientific reports

Zhao J,Sun Y,Huang Y,Song F,Huang Z,Bao Y,Zuo J,Saffen D,Shao Z,Liu W,Wang Y

Mon Jan 16 00:00:00 EST 2017

Thymoquinone Attenuates Brain Injury via an Anti-oxidative Pathway in a Status Epilepticus Rat Model.

Translational neuroscience

Shao YY,Li B,Huang YM,Luo Q,Xie YM,Chen YH

Sun Jan 01 00:00:00 EST 2017

Protective Effects of Thymoquinone Against Convulsant Activity Induced by Lithium-Pilocarpine in a model of Status Epilepticus.

Neurochemical research

Shao Y,Feng Y,Xie Y,Luo Q,Chen L,Li B,Chen Y

Thu Dec 01 00:00:00 EST 2016

Anxa5 mediates the in vitro malignant behaviours of murine hepatocarcinoma Hca-F cells with high lymph node metastasis potential preferentially via ERK2/p-ERK2/c-Jun/p-c-Jun(Ser73) and E-cadherin.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Sun X,Wei B,Liu S,Guo C,Wu N,Liu Q,Sun MZ

Thu Dec 01 00:00:00 EST 2016

Etomidate inhibits nuclear factor-κB through decreased expression of glucocorticoid receptor in septic rats.

Molecular medicine reports

Zhang Y,Li RM,Wang C,Liu N,Lv S,Xiong JY

Thu Dec 01 00:00:00 EST 2016

Polypeptide N-Acetylgalactosaminyltransferase 13 Contributes to Neurogenesis via Stabilizing the Mucin-type O-Glycoprotein Podoplanin.

The Journal of biological chemistry

Xu Y,Pang W,Lu J,Shan A,Zhang Y

Fri Nov 04 00:00:00 EDT 2016

NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis.

Scientific reports

Shen J,Wang L,Jiang N,Mou S,Zhang M,Gu L,Shao X,Wang Q,Qi C,Li S,Wang W,Che X,Ni Z

Mon Oct 10 00:00:00 EDT 2016

Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.

Experimental cell research

Zhang P,Chen L,Song Y,Li X,Sun Y,Xiao Y,Xing Y

Sat Oct 01 00:00:00 EDT 2016

MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.

Oncology reports

Chen L,Zhang F,Sheng XG,Zhang SQ,Chen YT,Liu BW

Sat Oct 01 00:00:00 EDT 2016

Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.

General and comparative endocrinology

Wang N,Guo DY,Tian X,Lin HP,Li YP,Chen SJ,Fu YC,Xu WC,Wei CJ

Sat Oct 01 00:00:00 EDT 2016

Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells.

Autophagy

Zhao X,Fang Y,Yang Y,Qin Y,Wu P,Wang T,Lai H,Meng L,Wang D,Zheng Z,Lu X,Zhang H,Gao Q,Zhou J,Ma D

Tue Sep 13 00:00:00 EDT 2016

Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.

Integrative biology : quantitative biosciences from nano to macro

Jin M,Yu B,Zhang W,Zhang W,Xiao Z,Mao Z,Lai Y,Lin D,Ma Q,Pan E,Zhang Y,Yu Y

Mon Sep 12 00:00:00 EDT 2016

Rabies virus inactivates cofilin to facilitate viral budding and release.

Biochemical and biophysical research communications

Zan J,An ST,Mo KK,Zhou JW,Liu J,Wang HL,Yan Y,Liao M,Zhou JY

Fri Sep 02 00:00:00 EDT 2016

Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.

Cell death & disease

Wu J,Guo W,Lin SZ,Wang ZJ,Kan JT,Chen SY,Zhu YZ

Thu Aug 18 00:00:00 EDT 2016

Pigment Epithelium-Derived Factor Induces Endothelial Barrier Dysfunction via p38/MAPK Phosphorylation.

BioMed research international

He T,Zhao L,Zhang D,Zhang Q,Jia J,Hu J,Huang Y

Wed Aug 17 00:00:00 EDT 2016

The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner.

Cancer research

Liu X,Chen L,Ge J,Yan C,Huang Z,Hu J,Wen C,Li M,Huang D,Qiu Y,Hao H,Yuan R,Lei J,Yu X,Shao J

Mon Aug 15 00:00:00 EDT 2016

Inhibition of histone deacetylases induces formation of multipolar spindles and subsequent p53-dependent apoptosis in nasopharyngeal carcinoma cells.

Oncotarget

Yan M,Qian YM,Yue CF,Wang ZF,Wang BC,Zhang W,Zheng FM,Liu Q

Tue Jul 12 00:00:00 EDT 2016

miR-1301 promotes prostate cancer proliferation through directly targeting PPP2R2C.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Bi D,Ning H,Liu S,Que X,Ding K

Fri Jul 01 00:00:00 EDT 2016

MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.

Protein & cell

Zhang Y,Chen M,Qiu Z,Hu K,McGee W,Chen X,Liu J,Zhu L,Wu JY

Fri Jul 01 00:00:00 EDT 2016

Go is required for the release of IL-8 and TNF-α, but not degranulation in human mast cells.

European journal of pharmacology

Yu Y,Huang Z,Mao Z,Zhang Y,Jin M,Chen W,Zhang W,Yu B,Zhang W,Alaster Lau HY

Sun Jun 05 00:00:00 EDT 2016

Deletion of Brg1 causes abnormal hair cell planer polarity, hair cell anchorage, and scar formation in mouse cochlea.

Scientific reports

Jin Y,Ren N,Li S,Fu X,Sun X,Men Y,Xu Z,Zhang J,Xie Y,Xia M,Gao J

Fri Jun 03 00:00:00 EDT 2016

CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.

RNA (New York, N.Y.)

Masamha CP,Xia Z,Peart N,Collum S,Li W,Wagner EJ,Shyu AB

Wed Jun 01 00:00:00 EDT 2016

Renalase attenuates hypertension, renal injury and cardiac remodelling in rats with subtotal nephrectomy.

Journal of cellular and molecular medicine

Yin J,Lu Z,Wang F,Jiang Z,Lu L,Miao N,Wang N

Wed Jun 01 00:00:00 EDT 2016

CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.

Oncotarget

Wen Q,Wang W,Luo J,Chu S,Chen L,Xu L,Zang H,Alnemah MM,Ma J,Fan S

Tue May 10 00:00:00 EDT 2016

Premutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.

Frontiers in neuroscience

Napoli E,Ross-Inta C,Song G,Wong S,Hagerman R,Gane LW,Smilowitz JT,Tassone F,Giulivi C

Thu May 05 00:00:00 EDT 2016

Characterization of Brain-Penetrant Pyrimidine-Containing Molecules with Differential Microtubule-Stabilizing Activities Developed as Potential Therapeutic Agents for Alzheimer's Disease and Related Tauopathies.

The Journal of pharmacology and experimental therapeutics

Kovalevich J,Cornec AS,Yao Y,James M,Crowe A,Lee VM,Trojanowski JQ,Smith AB,Ballatore C,Brunden KR

Sun May 01 00:00:00 EDT 2016

ZBTB20 is required for anterior pituitary development and lactotrope specification.

Nature communications

Cao D,Ma X,Cai J,Luan J,Liu AJ,Yang R,Cao Y,Zhu X,Zhang H,Chen YX,Shi Y,Shi GX,Zou D,Cao X,Grusby MJ,Xie Z,Zhang WJ

Fri Apr 15 00:00:00 EDT 2016

Loss-of-function Mutation in PMVK Causes Autosomal Dominant Disseminated Superficial Porokeratosis.

Scientific reports

Wang J,Liu Y,Liu F,Huang C,Han S,Lv Y,Liu CJ,Zhang S,Qin Y,Ling L,Gao M,Yu S,Li C,Huang M,Liao S,Hu X,Lu Z,Liu X,Jiang T,Tang Z,Zhang H,Guo AY,Liu M

Thu Apr 07 00:00:00 EDT 2016

Pdcd4 restrains the self-renewal and white-to-beige transdifferentiation of adipose-derived stem cells.

Cell death & disease

Bai Y,Shang Q,Zhao H,Pan Z,Guo C,Zhang L,Wang Q

Thu Mar 31 00:00:00 EDT 2016

Cell Autonomous and Nonautonomous Function of CUL4B in Mouse Spermatogenesis.

The Journal of biological chemistry

Yin Y,Liu L,Yang C,Lin C,Veith GM,Wang C,Sutovsky P,Zhou P,Ma L

Fri Mar 25 00:00:00 EDT 2016

PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata.

Scientific reports

Shi Y,He MX

Thu Feb 25 00:00:00 EST 2016

Spatially coordinated dynamic gene transcription in living pituitary tissue.

eLife

Featherstone K,Hey K,Momiji H,McNamara AV,Patist AL,Woodburn J,Spiller DG,Christian HC,McNeilly AS,Mullins JJ,Finkenstädt BF,Rand DA,White MR,Davis JR

Mon Feb 01 00:00:00 EST 2016

Cytoplasmic hnRNPK interacts with GSK3β and is essential for the osteoclast differentiation.

Scientific reports

Fan X,Xiong H,Wei J,Gao X,Feng Y,Liu X,Zhang G,He QY,Xu J,Liu L

Mon Dec 07 00:00:00 EST 2015

Real Time Monitoring of Inhibition of Adipogenesis and Angiogenesis by (-)-Epigallocatechin-3-Gallate in 3T3-L1 Adipocytes and Human Umbilical Vein Endothelial Cells.

Nutrients

Tang W,Song H,Cai W,Shen X

Tue Oct 27 00:00:00 EDT 2015

The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma.

Applied microbiology and biotechnology

Lin C,Wang Z,Li L,He Y,Fan J,Liu Z,Zhao S,Ju D

Thu Oct 01 00:00:00 EDT 2015

Adipose-derived mesenchymal stem cells promote cell proliferation and invasion of epithelial ovarian cancer.

Experimental cell research

Chu Y,Tang H,Guo Y,Guo J,Huang B,Fang F,Cai J,Wang Z

Thu Sep 10 00:00:00 EDT 2015

High expression of transforming acidic coiled coil-containing protein 3 strongly correlates with aggressive characteristics and poor prognosis of gastric cancer.

Oncology reports

Yun M,Rong J,Lin ZR,He YL,Zhang JX,Peng ZW,Tang LQ,Zeng MS,Zhong Q,Ye S

Tue Sep 01 00:00:00 EDT 2015

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.

Scientific reports

Zeng Y,Liu H,Kang K,Wang Z,Hui G,Zhang X,Zhong J,Peng W,Ramchandran R,Raj JU,Gou D

Mon Jul 13 00:00:00 EDT 2015

Bipartite Nuclear Localization Signal Controls Nuclear Import and DNA-Binding Activity of IFN Regulatory Factor 3.

Journal of immunology (Baltimore, Md. : 1950)

Zhu M,Fang T,Li S,Meng K,Guo D

Wed Jul 01 00:00:00 EDT 2015

Proteomic characterization of the nucleolar linker histone H1 interaction network.

Journal of molecular biology

Szerlong HJ,Herman JA,Krause CM,DeLuca JG,Skoultchi A,Winger QA,Prenni JE,Hansen JC

Fri Jun 05 00:00:00 EDT 2015

IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.

Cancer letters

Yuan L,Zhou C,Lu Y,Hong M,Zhang Z,Zhang Z,Chang Y,Zhang C,Li X

Wed Apr 01 00:00:00 EDT 2015

P38/MAPK contributes to endothelial barrier dysfunction via MAP4 phosphorylation-dependent microtubule disassembly in inflammation-induced acute lung injury.

Scientific reports

Li L,Hu J,He T,Zhang Q,Yang X,Lan X,Zhang D,Mei H,Chen B,Huang Y

Mon Mar 09 00:00:00 EDT 2015

Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.

PloS one

Frohnert C,Hutten S,Wälde S,Nath A,Kehlenbach RH

Fri Jan 02 00:00:00 EST 2015

Shear-sensitive microRNA-34a modulates flow-dependent regulation of endothelial inflammation.

Journal of cell science

Fan W,Fang R,Wu X,Liu J,Feng M,Dai G,Chen G,Wu G

Thu Jan 01 00:00:00 EST 2015

MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism.

Mitochondrion

Aras S,Bai M,Lee I,Springett R,Hüttemann M,Grossman LI

Thu Jan 01 00:00:00 EST 2015

Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells.

Journal of cellular biochemistry

Xue Y,Yan Y,Gong H,Fang B,Zhou Y,Ding Z,Yin P,Zhang G,Ye Y,Yang C,Ge J,Zou Y

Mon Sep 01 00:00:00 EDT 2014

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.

Biomaterials

Wang S,Li Y,Fan J,Wang Z,Zeng X,Sun Y,Song P,Ju D

Fri Aug 01 00:00:00 EDT 2014

Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine

Wu J,Chen W,Yin Y,Zheng Z,Zou G

Sun Jun 01 00:00:00 EDT 2014

Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locus.

Molecular endocrinology (Baltimore, Md.)

McEachern LA,Murphy PR

Tue Apr 01 00:00:00 EDT 2014

Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy.

Proceedings of the National Academy of Sciences of the United States of America

Schulz O,Pieper C,Clever M,Pfaff J,Ruhlandt A,Kehlenbach RH,Wouters FS,Großhans J,Bunt G,Enderlein J

Tue Dec 24 00:00:00 EST 2013

Pin1 promotes GR transactivation by enhancing recruitment to target genes.

Nucleic acids research

Poolman TM,Farrow SN,Matthews L,Loudon AS,Ray DW

Tue Oct 01 00:00:00 EDT 2013

Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry.

Molecular & cellular proteomics : MCP

Thakar K,Karaca S,Port SA,Urlaub H,Kehlenbach RH

Fri Mar 01 00:00:00 EST 2013

Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1.

The Journal of biological chemistry

Roloff S,Spillner C,Kehlenbach RH

Fri Feb 08 00:00:00 EST 2013

Long-distance intercellular connectivity between cardiomyocytes and cardiofibroblasts mediated by membrane nanotubes.

Cardiovascular research

He K,Shi X,Zhang X,Dang S,Ma X,Liu F,Xu M,Lv Z,Han D,Fang X,Zhang Y

Sat Oct 01 00:00:00 EDT 2011

Regulation of FGF-2 by an endogenous antisense RNA: effects on cell adhesion and cell-cycle progression.

Molecular carcinogenesis

MacFarlane LA,Murphy PR

Wed Dec 01 00:00:00 EST 2010

Intercellular transportation of quantum dots mediated by membrane nanotubes.

ACS nano

He K,Luo W,Zhang Y,Liu F,Liu D,Xu L,Qin L,Xiong C,Lu Z,Fang X,Zhang Y

Tue Jun 22 00:00:00 EDT 2010

Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.

Molecular endocrinology (Baltimore, Md.)

MacFarlane LA,Gu Y,Casson AG,Murphy PR

Thu Apr 01 00:00:00 EDT 2010

CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells.

The Journal of biological chemistry

Li GD,Zhang X,Li R,Wang YD,Wang YL,Han KJ,Qian XP,Yang CG,Liu P,Wei Q,Chen WF,Zhang J,Zhang Y

Fri Nov 21 00:00:00 EST 2008

Bioinformatics

Protein Aliases: alpha tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3E; Alpha-tubulin 4; Alpha-tubulin 6; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; Alpha-tubulin isotype M-alpha-6; Alpha-tubulin ubiquitous; Detyrosinated tubulin alpha-1A chain; Detyrosinated tubulin alpha-1B chain; Detyrosinated tubulin alpha-1C chain; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3E chain; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; Talpha1 alpha-tubulin; Testis-specific alpha-tubulin; TUBA1/3/4; Tubulin alpha; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-1B chain; Tubulin alpha-1C chain; Tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; Tubulin alpha-3E chain; Tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-6 chain; Tubulin alpha-ubiquitous chain; Tubulin B-alpha-1; Tubulin H2-alpha; Tubulin K-alpha-1; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous

Gene Aliases: ALS22; B-ALPHA-1; bA408E5.3; bcm948; H2-ALPHA; K-ALPHA-1; LIS3; M[a]4; M[a]6; RGD1565476; Tuba-1; TUBA1; TUBA1A; TUBA1B; TUBA1C; TUBA2; TUBA3; TUBA3C; TUBA3E; Tuba4; TUBA4A; TUBA6

UniProt ID: (Human) Q71U36, (Human) P68363, (Human) Q9BQE3, (Human) P0DPH7, (Human) Q6PEY2, (Human) P68366, (Mouse) P68369, (Rat) P68370, (Mouse) P05213, (Rat) Q6P9V9, (Mouse) P68373, (Rat) Q6AYZ1, (Mouse) P68368, (Rat) Q5XIF6