PA5-28808 targets beta 1 Adrenergic Receptor in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28808 immunogen is synthetic peptide corresponding to a region within amino acids 414 and 477 of Human beta 1 Adrenergic Receptor.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
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Protein Aliases: ADRB1R; adrenergic receptor, beta 1; adrenergic, beta-1-, receptor; B1AR; beta 1-adrenergic receptor beta 1-AR; beta 1-AR; Beta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor; BETA1AR; cardiac beta adrenergic receptor; RHR
Gene Aliases: Adrb-1; ADRB1; ADRB1R; B1AR; beta-AR; BETA1AR; RATB1AR; RHR