Western blot analysis of beta-2 Adrenergic Receptor in E coli-derived fusion protein. Samples were probed with a beta-2 Adrenergic Receptor polyclonal antibody (Product # PA1-25659) at a dilution of 1:2000 and a Goat anti-IgY-HRP secondary antibody at a dilution of 1:1000. Colorimetric method was used for signal development.
|Tested species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptide corresponding to residues 335-408 of human beta 2 Adrenergic Receptor.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
PA1-25659 detects beta 2 Adrenergic Receptor from human samples.
PA1-25659 has been successfully used in Western blot procedures.
The PA1-25659 immunogen is a synthetic peptide corresponding to residues 335-408 of human beta 2 Adrenergic Receptor.
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.