|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The immunogen is within aa1- 20 of human beta 3 Adrenergic receptor|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20715 detects beta-3 adrenergic receptor in human samples.
PA1-20715 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-20715 immunogen corresponds to an epitope within aa 1- 20 of human beta 3 Adrenergic receptor.
beta 3 Adrenergic Receptor is located mainly in adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Beta adrenergic receptors are involved in the epenephrine and norepinephrine-induced activation of adenylate cyclase through the action of G proteins. beta 3 Adrenergic Receptor expression has been documented in adipose tissues, heart, and in smooth muscle of digestive and urinary tract organs (bladder, colon, small intestine, stomach, ureter). Utilization of alternate promoters and/or 3-prime untranslated regions may result in tissue-specific regulation of the expression of this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.