Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
10 µg/mL | - |
Immunohistochemistry (Frozen) (IHC (F)) |
10 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Hamster, Rabbit, Rat |
Published species |
Rat |
Host/Isotype |
Sheep / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide corresponding to the N-terminal residues M(2) F S G F N A D Y E A S S S R C(17). |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
1 mg/mL |
Purification |
Protein G |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_1073602 |
PA1-18329 detects c-FOS from rat, rabbit, and hamster samples.
PA1-18329 has been successfully used in immunohistochemistry (paraffin and frozen) and Western blot procedures.
The PA1-18329 immunogen is a synthetic peptide corresponding to the N-terminal residues M(2) F S G F N A D Y E A S S S R C(17), conjugated to diphtheria toxoid. The sequence is 100% conserved in human, rat, mouse, hamster, and cat.
Reconstitute with 500 µL of distilled water.
FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: c-fos oncogene; c-fos protooncogene protein; Cellular oncogene fos; FBJ murine osteosarcoma viral oncogene homolog; FBJ osteosarcoma oncogene; Proto-oncogene c-Fos; proto-oncogene cFOS; Proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Aliases: c-fos; FOS; I79_009428
UniProt ID: (Chinese hamster) Q9Z2Q8, (Rat) P12841
Entrez Gene ID: (Rabbit) 100338345, (Chinese hamster) 100689418, (Rat) 314322
Molecular Function:
basic leucine zipper transcription factor
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
