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c-Myb Antibody (A304-137A) in IHC (P)
Detection of human c-Myb by immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and salivary gland (right). Antibody: Affinity purified rabbit anti-c-Myb (Product # A304-137A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.
Product Details
A304-137A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 225 to 275 of human V-myb Myeloblastosis Viral Oncogene Homolog.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.^M
^M
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
Gene Aliases: c-myb; c-myb_CDS; Cmyb; efg; MYB
UniProt ID: (Human) P10242
Entrez Gene ID: (Human) 4602
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, RNA polymerase II transcription factor recruiting
protein binding
negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
chromatin remodeling
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of T-helper cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
positive regulation of histone H3-K9 methylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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