This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-29085 targets cIAP1 in WB applications and shows reactivity with Human, Rat, and mouse samples.
The PA5-29085 immunogen is recombinant fragment corresponding to a region within amino acids 316 and 595 of Human cIAP1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
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Protein Aliases: API1; apoptosis inhibitor 1; apoptosis inhibitor 2; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; Baculoviral IAP repeat-containing protein 2; C-IAP1; Cellular inhibitor of apoptosis 1; cIAP1; Hiap-2; HIAP2; IAP homolog B; IAP-2; inhibitor of apoptosis protein; Inhibitor of apoptosis protein 2; mIAP-2; mIAP2; MIHB; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; RNF48; TNFR2-TRAF-signaling complex protein 2
Gene Aliases: API1; Api2; AW146227; BIRC2; Birc3; c-IAP1; cIAP1; cIAP2; Hiap-2; HIAP1; HIAP2; IAP1; IAP2; mcIAP1; MIAP1; MIAP2; MIHB; MIHC; rIAP1; RNF48