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Bethyl Laboratories
ch-TOG Polyclonal Antibody
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FIGURE: 1 / 3
ch-TOG Antibody (A301-970A) in WB
Detection of human ch-TOG by western blot. Samples: Whole cell lysate (50 µg) from U2OS, K-562, Jurkat, HEK293T, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-ch-TOG antibody (Product # A301-970A) (lot A301-970A-1) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A301-970A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1425 and 1475 of human colonic and hepatic tumor over-expressed protein.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
Colonic and hepatic tumor over-expressed protein (ch-TOG) belongs to the TOG/XMAP215/Dis1 evolutionarily ancient family of microtubule-associated proteins with isoforms found in all major kingdoms of eukaryotes. This protein is required for the assembly and function of the meiotic or mitotic spindles during cell division and is localized to microtubule-organizing centers (MTOCs) during interphase or to the spindle poles and centrosomes during mitosis or cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ch-TOG; ch-TOGp; ckap5; colonic and hepatic tumor over-expressed gene protein; Colonic and hepatic tumor overexpressed gene protein; Cytoskeleton-associated protein 5; unnamed protein product
Gene Aliases: 3110043H24Rik; 4930432B04Rik; ch-TOG; CHTOG; CKAP5; D730027C18Rik; KIAA0097; mKIAA0097; MSPS; T25636; TOG; TOGp
UniProt ID: (Human) Q14008, (Mouse) A2AGT5
Entrez Gene ID: (Human) 9793, (Mouse) 75786
microtubule depolymerization
spindle organization
mitotic spindle organization
centrosome cycle
establishment or maintenance of microtubule cytoskeleton polarity
protein-containing complex subunit organization
microtubule polymerization
RNA transport
centrosome duplication
cell division
positive regulation of microtubule nucleation
cell cycle
mitotic nuclear division
centrosome organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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