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Bethyl Laboratories
eIF2B5 Polyclonal Antibody
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Product Details
IHC-00709
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 550 and 600 of human eukaryotic translation initiation factor 2B, subunit 5 epsilon.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and Chinese hamster
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; translation initiation factor eIF-2B subunit epsilon; Translation initiation factor eIF2B subunit epsilon; unnamed protein product
Gene Aliases: CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM; VWM5
UniProt ID: (Human) Q13144
Entrez Gene ID: (Human) 8893
ovarian follicle development
cytoplasmic translational initiation
translation
translational initiation
response to heat
response to glucose
astrocyte development
oligodendrocyte development
hippocampus development
response to endoplasmic reticulum stress
myelination
positive regulation of apoptotic process
response to peptide hormone
positive regulation of translation
positive regulation of translational initiation
astrocyte differentiation
T cell receptor signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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