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Product Details
PA5-65564
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human eIF2b alpha. Recombinant protein control fragment (Product #RP-104873).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663288
Product Specific Information
Immunogen sequence: AKAQNKPFYVV AESFKFVRLF PLNQQDVPDK FKYKADTLKV AQTGQDLKEE HPWVDYTAPS LITLLFTDLG VLTPSAVSDE LIKLYL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Translation initiation factor eIF2B subunit alpha
Gene Aliases: EIF2B; EIF2B1; EIF2BA
UniProt ID: (Human) Q14232
Entrez Gene ID: (Human) 1967
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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