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Invitrogen
eIF2b alpha Polyclonal Antibody
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Product Details
PA5-76295
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein of human EIF2B1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B; eIF-2B GDP-GTP exchange factor subunit alpha; eIF2B GDP-GTP exchange factor subunit alpha; EIF2B1; eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa); eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; translation initiation factor eIF-2B subunit alpha; Translation initiation factor eIF2B subunit alpha; unnamed protein product
Gene Aliases: 26kDa; D5Ertd406e; EIF2B; EIF2B1; EIF2BA; EIF2Balpha; VWM1
UniProt ID: (Human) Q14232, (Mouse) Q99LC8
Entrez Gene ID: (Human) 1967, (Mouse) 209354
cytoplasmic translational initiation
translation
translational initiation
response to heat
response to glucose
oligodendrocyte development
response to peptide hormone
T cell receptor signaling pathway
regulation of translation
regulation of translational initiation
negative regulation of translational initiation in response to stress
positive regulation of GTPase activity
cellular metabolic process
cellular response to stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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