PA5-30223 targets EIF5 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30223 immunogen is recombinant protein fragment corresponding to a region within amino acids 184 and 415 of Human EIF5.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).
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Protein Aliases: eIF-5; EIF-5A; eukaryotic initiation factor 5 (eIF-5); Eukaryotic translation initiation factor 5
Gene Aliases: 2810011H21Rik; D12Ertd549e; EIF-5; EIF-5A; EIF5