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FIGURE: 1 / 1
Positive test controls include: U-87MG, SKOV3, SW480, THP-1, Mouse lung, Mouse brain, Mouse spleen, Rat lung. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Nucleus, Peripheral membrane protein, nuclear pore complex.
Immunogen sequence: MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDYQ LICIQDGYLS LLTETGEVRE DLKLPEGELG KEIEGKYNAG EDVQVSVMCA MSEEYAVAIK PCK
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-5A-2; eIF-5A2; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 2; Eukaryotic translation initiation factor 5A-2
Gene Aliases: 9630038B20; EIF-5A2; EIF5A2; eIF5AII
UniProt ID: (Human) Q9GZV4, (Mouse) Q8BGY2
Entrez Gene ID: (Human) 56648, (Rat) 310261, (Mouse) 208691
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