Recommended positive controls: 293T, A431, HeLa.
Predicted reactivity: Mouse (100%), Rat (100%), Chicken (91%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: eIF-5A-2; eukaryotic initiation factor 5A; Eukaryotic initiation factor 5A isoform 2; Eukaryotic translation initiation factor 5A-2
Gene Aliases: EIF-5A2; EIF5A2; eIF5AII
UniProt ID: (Human) Q9GZV4
Entrez Gene ID: (Human) 56648
Molecular Function: translation initiation factor