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Invitrogen
gamma Catenin Recombinant Rabbit Monoclonal Antibody (9O2K8)
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Product Details
MA5-35452
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
9O2K8
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 15-115 of human gamma-Catenin (P14923)
Conjugate
Form
Liquid
Concentration
1.35 mg/mL
Amount
135 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EWQQTYTYDS GIHSGANTCV PSVSSKGIME EDEACGRQYT LKKTTTYTQG VPPSQGDLEY QMSTTARAKR VREAMCPGVS GEDSSLLLAT QVEGQATNLQ R
Target Information
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; desmosomal protein 3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735
Gene Aliases: CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB
UniProt ID: (Human) P14923, (Rat) Q6P0K8, (Mouse) Q02257
Entrez Gene ID: (Human) 3728, (Rat) 81679, (Mouse) 16480
transcription coactivator activity
structural molecule activity
protein binding
ligand-dependent nuclear receptor binding
protein phosphatase binding
protein homodimerization activity
alpha-catenin binding
cadherin binding
cell adhesion molecule binding
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
microtubule cortical anchor activity
signal transducer activity
protein kinase binding
nuclear hormone receptor binding
positive regulation of cell-matrix adhesion
desmosome assembly
cell adhesion
cell migration
regulation of cell proliferation
positive regulation of protein import into nucleus
negative regulation of blood vessel endothelial cell migration
skin development
positive regulation of angiogenesis
positive regulation of transcription from RNA polymerase II promoter
detection of mechanical stimulus
canonical Wnt signaling pathway
endothelial cell-cell adhesion
cellular response to indole-3-methanol
protein localization to plasma membrane
bundle of His cell-Purkinje myocyte adhesion involved in cell communication
regulation of heart rate by cardiac conduction
positive regulation of canonical Wnt signaling pathway
cell-cell adhesion
regulation of ventricular cardiac muscle cell action potential
signal transduction
single organismal cell-cell adhesion
adherens junction assembly
regulation of cell fate specification
positive regulation of sequence-specific DNA binding transcription factor activity
protein heterooligomerization
ventricular cardiac muscle cell action potential
bundle of His cell to Purkinje myocyte communication
establishment of protein localization to plasma membrane
regulation of nucleic acid-templated transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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