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hCV-2 Antibody (PA5-47295) in IHC (F)
Immunohistochemical analysis of hCV-2 in immersion fixed frozen sections of mouse embryo (E13.5). Samples were incubated with hCV-2 polyclonal antibody (Product # PA5-47295) using a dilution of 10 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to the epithelium surrounding the nasa... View More
Product Details
PA5-47295
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Crossveinless-2/CV-2 Ala39-Arg685
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606893
Product Specific Information
In Western blots, approximately 50% cross-reactivity with recombinant human CV-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
BMPER contains 1 TIL (trypsin inhibitory-like) domain, 5 VWFC domains and 1 VWFD domain.BMPER is the inhibitor of bone morphogenetic protein (BMP) functions. It may regulate BMP responsiveness of osteoblasts and chondrocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP-binding endothelial regulator protein; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; crossveinless-2; mCV2; Protein crossveinless-2
Gene Aliases: 3110056H04Rik; Bmper; Crim3; CV-2; Cv2
UniProt ID: (Mouse) Q8CJ69
Entrez Gene ID: (Mouse) 73230
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
regulation of endothelial cell migration
negative regulation of BMP signaling pathway
endothelial cell activation
endothelial cell differentiation
inner ear development
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of ERK1 and ERK2 cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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