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Agrisera
hScrib/Protein LAP4 Polyclonal Antibody
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Product Details
AS06-155
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
GST tagged C-terminus of hScrib including PDZ3 and 4 domains.
Conjugate
Form
Lyophilized
Storage buffer
whole serum
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 100 µL of sterile water.
Specific Species Reactivity: Human
Target Information
SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adaptor protein; CRIB1; hScrib; hSCRIB1-N1; KIAA0147; oSCRIB; Protein LAP4; Protein scribble homolog; S Vartul; SCRB1; SCRIB1; Scribble; scribbled homolog; scribbled planar cell polarity protein; Vartul
Gene Aliases: CRIB1; KIAA0147; LAP4; oSCRIB; SCRB1; SCRIB; SCRIB1; VARTUL
UniProt ID: (Human) Q14160
Entrez Gene ID: (Human) 23513
establishment of T cell polarity
neural tube closure
positive regulation of receptor recycling
auditory receptor cell morphogenesis
regulation of translation
protein localization
cell proliferation
epithelial structure maintenance
positive regulation of epithelial to mesenchymal transition
synaptic vesicle targeting
morphogenesis of embryonic epithelium
cell migration
cochlear nucleus development
establishment of cell polarity
cell differentiation
polarized epithelial cell differentiation
positive regulation of interferon-gamma production
establishment or maintenance of apical/basal cell polarity
establishment of apical/basal cell polarity
post-anal tail morphogenesis
wound healing
positive regulation of apoptotic process
receptor clustering
astrocyte cell migration
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
negative regulation of translational initiation
negative regulation of activated T cell proliferation
synaptic vesicle endocytosis
positive chemotaxis
auditory receptor cell stereocilium organization
inner ear receptor stereocilium organization
apoptotic process involved in morphogenesis
mammary gland duct morphogenesis
protein localization to adherens junction
activation of GTPase activity
cell-cell adhesion
neurotransmitter receptor transport, endosome to postsynaptic membrane
vesicle-mediated transport in synapse
regulation of postsynaptic neurotransmitter receptor internalization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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