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Huabio
mGluR6 Polyclonal Antibody
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FIGURE: 1 / 2
mGluR6 Antibody (HA500158) in WB
Western blot analysis of mGluR6 on HepG2 cell lysate. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (HA500158, 1:1,000) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:200,000 dilution was used for 1 hour at room temperature.
Product Details
HA500158
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human mGluR6 aa 820-877.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glutamate receptor; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 6; mGluR6
Gene Aliases: CSNB1B; GPRC1F; GRM6; mGlu6; MGLUR6
UniProt ID: (Human) O15303
Entrez Gene ID: (Human) 2916
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
synapse assembly
visual perception
locomotory behavior
detection of visible light
gene expression
detection of light stimulus involved in visual perception
sensory perception of light stimulus
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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