Product References
PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation.
OncoTargets and therapy
Lv JM,Chen L,Gao Y,Huang H,Pan XW,Liu X,Chen M,Qu FJ,Li L,Wang JK,Cui XG,Xu DF
Mon Mar 21 00:00:00 EDT 2022
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
American journal of cancer research
Li D,Qu C,Ning Z,Wang H,Zang K,Zhuang L,Chen L,Wang P,Meng Z
Thu Oct 01 00:00:00 EDT 2020
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
American journal of translational research
Chen T,Zhu H,Wang Y,Zhao P,Chen J,Sun J,Zhang X,Zhu G
Wed Sep 30 00:00:00 EDT 2020
Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes.
Frontiers in pharmacology
Liang S,Lv ZT,Zhang JM,Wang YT,Dong YH,Wang ZG,Chen K,Cheng P,Yang Q,Guo FJ,Lu WW,Zhu WT,Chen AM
Tue Sep 29 00:00:00 EDT 2020
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Cancer biology & therapy
Fan Y,Li M,Ma K,Hu Y,Jing J,Shi Y,Li E,Dong D
Mon Jul 06 00:00:00 EDT 2020
Intermedin in Paraventricular Nucleus Attenuates Sympathoexcitation and Decreases TLR4-Mediated Sympathetic Activation via Adrenomedullin Receptors in Rats with Obesity-Related Hypertension.
Neuroscience bulletin
Sun J,Ren XS,Kang Y,Dai HB,Ding L,Tong N,Zhu GQ,Zhou YB
Fri Feb 01 00:00:00 EST 2019
Activation of the Omega-3 Fatty Acid Receptor GPR120 Protects against Focal Cerebral Ischemic Injury by Preventing Inflammation and Apoptosis in Mice.
Journal of immunology (Baltimore, Md. : 1950)
Ren Z,Chen L,Wang Y,Wei X,Zeng S,Zheng Y,Gao C,Liu H
Fri Feb 01 00:00:00 EST 2019
The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Zhang Y,Sun Y,Peng R,Liu H,He W,Zhang L,Peng H,Zhang Z
Fri Jan 25 00:00:00 EST 2019
PKP3 interactions with MAPK-JNK-ERK1/2-mTOR pathway regulates autophagy and invasion in ovarian cancer.
Biochemical and biophysical research communications
Lim V,Zhu H,Diao S,Hu L,Hu J
Tue Jan 08 00:00:00 EST 2019
Correlation of TGN-020 with the analgesic effects via ERK pathway activation after chronic constriction injury.
Molecular pain
Zhao L,Li D,Liu N,Liu L,Zhang Z,Gao C,Kawano H,Zhou FY,Li HP
Tue Dec 11 00:00:00 EST 2018
New insights into meningitic Escherichia coli infection of brain microvascular endothelial cells from quantitative proteomics analysis.
Journal of neuroinflammation
Liu WT,Lv YJ,Yang RC,Fu JY,Liu L,Wang H,Cao Q,Tan C,Chen HC,Wang XR
Fri Oct 19 00:00:00 EDT 2018
Prostaglandin F2α Facilitates Hepatic Glucose Production Through CaMKIIγ/p38/FOXO1 Signaling Pathway in Fasting and Obesity.
Diabetes
Wang Y,Yan S,Xiao B,Zuo S,Zhang Q,Chen G,Yu Y,Chen D,Liu Q,Liu Y,Shen Y,Yu Y
Sat Sep 01 00:00:00 EDT 2018
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo.
Free radical biology & medicine
Xiang L,Xu X,Zhang S,Cai D,Dai X
Mon Aug 20 00:00:00 EDT 2018
Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Lu X,Wei T,Dong Y,Cai Z,Tang L,Liu M
Thu Jul 12 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-α pathway in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lu X,Liu T,Chen K,Xia Y,Dai W,Xu S,Xu L,Wang F,Wu L,Li J,Li S,Wang W,Yu Q,Feng J,Fan X,Zhou Y,Niu P,Guo C
Sun Jul 01 00:00:00 EDT 2018
Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure.
Journal of ethnopharmacology
Chen L,Cao Y,Zhang H,Lv D,Zhao Y,Liu Y,Ye G,Chai Y
Tue Jun 12 00:00:00 EDT 2018
All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway.
Neurochemical research
Li M,Tian X,An R,Yang M,Zhang Q,Xiang F,Liu H,Wang Y,Xu L,Dong Z
Fri Jun 01 00:00:00 EDT 2018
Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice.
Drug design, development and therapy
Feng J,Zhang Q,Mo W,Wu L,Li S,Li J,Liu T,Xu S,Fan X,Guo C
Thu Apr 26 00:00:00 EDT 2018
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.
British journal of pharmacology
Leng YP,Ma YS,Li XG,Chen RF,Zeng PY,Li XH,Qiu CF,Li YP,Zhang Z,Chen AF
Sun Apr 01 00:00:00 EDT 2018
Neuroprotective Effect of Oxysophocarpine by Modulation of MAPK Pathway in Rat Hippocampal Neurons Subject to Oxygen-Glucose Deprivation and Reperfusion.
Cellular and molecular neurobiology
Zhao P,Chang RY,Liu N,Wang J,Zhou R,Qi X,Liu Y,Ma L,Niu Y,Sun T,Li YX,He YP,Yu JQ
Thu Mar 01 00:00:00 EST 2018
Scandoside Exerts Anti-Inflammatory Effect Via Suppressing NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages.
International journal of molecular sciences
He J,Li J,Liu H,Yang Z,Zhou F,Wei T,Dong Y,Xue H,Tang L,Liu M
Sat Feb 03 00:00:00 EST 2018
Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation.
Journal of molecular neuroscience : MN
Huang L,Chen C,Zhang X,Li X,Chen Z,Yang C,Liang X,Zhu G,Xu Z
Mon Jan 01 00:00:00 EST 2018
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhao B,Liu L,Mao J,Liu K,Fan W,Liu J,Zhang Z,Li Q
Fri Dec 01 00:00:00 EST 2017
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
Microbial pathogenesis
Chen L,Lai Y,Dong L,Kang S,Chen X
Fri Dec 01 00:00:00 EST 2017
The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity.
Scientific reports
Xu S,Niu P,Chen K,Xia Y,Yu Q,Liu N,Li J,Li S,Wu L,Feng J,Wang W,Lu X,Liu T,Wang F,Dai W,Fan X,Mo W,Xu L,Guo C
Thu Nov 09 00:00:00 EST 2017
Spiroplasma eriocheiris induces mouse 3T6-Swiss albino cell apoptosis that associated with the infection mechanism.
Molecular immunology
Hou L,Gu W,Zhu H,Yao W,Wang W,Meng Q
Wed Nov 01 00:00:00 EDT 2017
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways.
European journal of pharmacology
Chen HB,Luo CD,Liang JL,Zhang ZB,Lin GS,Wu JZ,Li CL,Tan LH,Yang XB,Su ZR,Xie JH,Zeng HF
Fri Sep 15 00:00:00 EDT 2017
Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites.
Scientific reports
Tang H,Yao X,Yao C,Zhao X,Zuo H,Li Z
Tue Aug 08 00:00:00 EDT 2017
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis.
Oncotarget
Fan L,Cao X,Yan H,Wang Q,Tian X,Zhang L,He X,Borjihan G
Tue Jul 18 00:00:00 EDT 2017
Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice.
Oncotarget
Yang Y,Gong XB,Huang LG,Wang ZX,Wan RZ,Zhang P,Zhang QY,Chen Z,Zhang BS
Tue May 09 00:00:00 EDT 2017
Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice.
International immunopharmacology
Gong X,Yang Y,Huang L,Zhang Q,Wan RZ,Zhang P,Zhang B
Mon May 01 00:00:00 EDT 2017
Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo.
Journal of neuroinflammation
Li D,Liu N,Zhao HH,Zhang X,Kawano H,Liu L,Zhao L,Li HP
Wed Mar 29 00:00:00 EDT 2017
Chemical characterization of a novel polysaccharide ASKP-1 from Artemisia sphaerocephala Krasch seed and its macrophage activation via MAPK, PI3k/Akt and NF-κB signaling pathways in RAW264.7 cells.
Food & function
Ren D,Lin D,Alim A,Zheng Q,Yang X
Wed Mar 22 00:00:00 EDT 2017
Protective effect of resveratrol against nigrostriatal pathway injury in striatum via JNK pathway.
Brain research
Li D,Liu N,Zhao L,Tong L,Kawano H,Yan HJ,Li HP
Sun Jan 01 00:00:00 EST 2017
Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mao Y,Wang J,Yu F,Li Z,Li H,Guo C,Fan X
Thu Dec 01 00:00:00 EST 2016
Charaterization and immunomodulatory activities of polysaccharide isolated from Pleurotus eryngii.
International journal of biological macromolecules
Xu D,Wang H,Zheng W,Gao Y,Wang M,Zhang Y,Gao Q
Tue Nov 01 00:00:00 EDT 2016
Paper-based microreactor array for rapid screening of cell signaling cascades.
Lab on a chip
Huang CH,Lei KF,Tsang NM
Sun Aug 07 00:00:00 EDT 2016
Preventive Effects of a Novel Polysaccharide from Sepia esculenta Ink on Ovarian Failure and Its Action Mechanisms in Cyclophosphamide-Treated Mice.
Journal of agricultural and food chemistry
Liu HZ,Tao YX,Luo P,Deng CM,Gu YP,Yang L,Zhong JP
Wed Jul 20 00:00:00 EDT 2016
Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3.
Toxicology letters
Gao Y,Yin Y,Xing X,Zhao Z,Lu Y,Sun Y,Zhuang Z,Wang M,Ji W,He Y
Fri Jul 08 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Zheng S,Yang C,Liu T,Liu Q,Dai F,Sheyhidin I,Lu X
Wed Jun 01 00:00:00 EDT 2016
RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway.
PloS one
Gu A,Jie Y,Sun L,Zhao S,E M,You Q
Mon May 23 00:00:00 EDT 2016
High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy.
Medical science monitor : international medical journal of experimental and clinical research
Zhang W,Sun J,Luo J
Tue May 10 00:00:00 EDT 2016
The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.
Cancer biology & therapy
Jin X,Mo Q,Zhang Y,Gao Y,Wu Y,Li J,Hao X,Ma D,Gao Q,Chen P
Tue May 03 00:00:00 EDT 2016
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Scientific reports
Li X,Yang J,Liu D,Li J,Niu K,Feng S,Yokota H,Zhang P
Mon Apr 18 00:00:00 EDT 2016
Neohesperidin Dihydrochalcone versus CCl₄-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation.
Journal of agricultural and food chemistry
Su C,Xia X,Shi Q,Song X,Fu J,Xiao C,Chen H,Lu B,Sun Z,Wu S,Yang S,Li X,Ye X,Song E,Song Y
Wed Jun 10 00:00:00 EDT 2015
Astaxanthin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy via the ROS/MAPK Pathway in Mice.
Marine drugs
Li J,Wang F,Xia Y,Dai W,Chen K,Li S,Liu T,Zheng Y,Wang J,Lu W,Zhou Y,Yin Q,Lu J,Zhou Y,Guo C
Wed May 27 00:00:00 EDT 2015
Polychlorinated biphenyl quinone induces endothelial barrier dysregulation by setting the cross talk between VE-cadherin, focal adhesion, and MAPK signaling.
American journal of physiology. Heart and circulatory physiology
Zhang P,Feng S,Bai H,Zeng P,Chen F,Wu C,Peng Y,Zhang Q,Zhang Q,Ye Q,Xue Q,Xu X,Song E,Song Y
Fri May 15 00:00:00 EDT 2015
Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells.
Medical oncology (Northwood, London, England)
Li X,Zou K,Gou J,Du Q,Li D,He X,Li Z
Sun Mar 01 00:00:00 EST 2015