Bioss

p47 Polyclonal Antibody

View all (24) Pleckstrin antibodies

Questions & Answers

Questions & Answers

Questions & Answers

Additional Information:

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Product Details

BS-9902R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Pleckstrin/p47.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Major protein kinase C substrate of platelets.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin; PLEK; unnamed protein product

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Gene Aliases: 2010300B13Rik; P47; PLEK; PLEK1

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UniProt ID: (Human) P08567, (Mouse) Q9JHK5, (Rat) Q4KM33

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Entrez Gene ID: (Human) 5341, (Mouse) 56193, (Rat) 364206

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protein kinase C binding protein binding phosphatase activator activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding cytoskeletal protein

hematopoietic progenitor cell differentiation platelet degranulation vesicle docking involved in exocytosis phospholipase C-activating G-protein coupled receptor signaling pathway integrin-mediated signaling pathway positive regulation of platelet activation negative regulation of inositol phosphate biosynthetic process cell projection organization actin cytoskeleton organization positive regulation of actin filament depolymerization phospholipase C-inhibiting G-protein coupled receptor signaling pathway cortical actin cytoskeleton organization ruffle organization positive regulation of actin filament bundle assembly positive regulation of integrin activation intracellular signal transduction inositol phosphate metabolic process positive regulation of cellular component biogenesis negative regulation of G-protein coupled receptor protein signaling pathway negative regulation of calcium-mediated signaling regulation of cell diameter thrombin receptor signaling pathway negative regulation of thrombin receptor signaling pathway platelet aggregation protein secretion by platelet positive regulation of inositol-polyphosphate 5-phosphatase activity actin cytoskeleton reorganization phosphatidylinositol metabolic process protein kinase C signaling

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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