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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues Q(13) P P G P E D E D S S L D E S D(28) of human p8.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4177 detects human p8 (com1).
PA1-4177 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~9 kDa protein representing Human p8 (com1) in HepGe cell lysates.
The PA1-4177 immunogen is a synthetic peptide corresponding to residues Q(13) P P G P E D E D S S L D E S D(28) of human p8.
The human p8 gene encodes a nuclear protein with strong mitogenic activity, which is expressed in the pancreas in response to acute pancreatitis. Response to TNF alpha and staurosporine-induced apoptosis is not modified by p8 expression. However, cells expressing p8 grow significantly and more rapidly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
60B8AG; CAGA; candidate of metastasis 1; CFAG; CGLA; CP-10; L1Ag; MA387; MRP8; NIF; nuclear protein, transcriptional regulator, 1; nuclear transcriptional regulator protein 1; P8; protein p8
COM1; NUPR1; P8