This antibody is predicted to react with rat samples based on sequence homology.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain tissue.
Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: alpha-synuclein, beta-synuclein, and gamma-synuclein. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors makes it a candidate as a marker for tumor progression.
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Protein Aliases: Alpha-synuclein; Beta-synuclein; Breast cancer-specific gene 1 protein; Gamma-synuclein; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; Persyn; SR; Synoretin; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); synuclein, gamma (breast cancer-specific protein 1)
Gene Aliases: BCSG1; NACP; PARK1; PARK4; PD1; PERSYN; PRSN; SNCA; SNCB; SNCG; SR