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proCNP Polyclonal Antibody
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Product Details
BS-1069R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human proCNP, amino acids 103-126.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-type natriuretic peptide; natriuretic peptide precursor C; natriuretic peptide precursor type C
Gene Aliases: CNP; CNP2; lbab; NPPC
UniProt ID: (Human) P23582, (Mouse) Q61839, (Rat) P55207
Entrez Gene ID: (Human) 4880, (Mouse) 18159, (Rat) 114593
ossification
angiogenesis
ovarian follicle development
cumulus cell differentiation
response to hypoxia
blood vessel remodeling
response to ischemia
growth plate cartilage chondrocyte differentiation
growth plate cartilage chondrocyte proliferation
cGMP biosynthetic process
protein folding
cellular calcium ion homeostasis
receptor guanylyl cyclase signaling pathway
negative regulation of cell proliferation
response to xenobiotic stimulus
response to wounding
post-embryonic development
positive regulation of cGMP-mediated signaling
cGMP-mediated signaling
negative regulation of collagen biosynthetic process
gastric emptying
response to decreased oxygen levels
regulation of multicellular organism growth
negative regulation of neuron apoptotic process
response to ethanol
positive regulation of osteoblast differentiation
animal organ development
oocyte development
regulation of smooth muscle cell proliferation
response to axon injury
chromosome organization
meiotic cell cycle
negative regulation of meiotic cell cycle
c-di-GMP signaling
multicellular organismal locomotion
response to oxygen-glucose deprivation
regulation of blood vessel diameter
bone growth
negative regulation of oocyte maturation
meiotic cell cycle process involved in oocyte maturation
cellular response to glycoprotein
negative regulation of DNA biosynthetic process
regulation of cAMP metabolic process
regulation of cGMP metabolic process
positive regulation of cGMP biosynthetic process
single organism reproductive process
positive regulation of vasodilation
regulation of blood vessel size
negative regulation of DNA metabolic process
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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