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          • Primary Antibodies ›
          • proCNP Antibodies

          Bioss

          proCNP Polyclonal Antibody

          View all (3) proCNP antibodies

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          Cite proCNP Polyclonal Antibody

          Additional Information:
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          proCNP Polyclonal Antibody

          Product Details

          BS-1069R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:400
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human proCNP, amino acids 103-126.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP; MIM 108780), brain natriuretic peptide (BNP; MIM 600295), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: C-type natriuretic peptide; natriuretic peptide precursor C; natriuretic peptide precursor type C

          View more View less

          Gene Aliases: CNP; CNP2; lbab; NPPC

          View more View less

          UniProt ID: (Human) P23582, (Mouse) Q61839, (Rat) P55207

          View more View less

          Entrez Gene ID: (Human) 4880, (Mouse) 18159, (Rat) 114593

          View more View less

          Function(s)
          receptor binding hormone activity guanylate cyclase activator activity hormone receptor binding neuropeptide hormone activity protein homodimerization activity peptide hormone receptor binding peptide hormone
          Process(es)
          ossification angiogenesis ovarian follicle development cumulus cell differentiation response to hypoxia blood vessel remodeling response to ischemia growth plate cartilage chondrocyte differentiation growth plate cartilage chondrocyte proliferation cGMP biosynthetic process protein folding cellular calcium ion homeostasis receptor guanylyl cyclase signaling pathway negative regulation of cell proliferation response to xenobiotic stimulus response to wounding post-embryonic development positive regulation of cGMP-mediated signaling cGMP-mediated signaling negative regulation of collagen biosynthetic process gastric emptying response to decreased oxygen levels regulation of multicellular organism growth negative regulation of neuron apoptotic process response to ethanol positive regulation of osteoblast differentiation animal organ development oocyte development regulation of smooth muscle cell proliferation response to axon injury chromosome organization meiotic cell cycle negative regulation of meiotic cell cycle c-di-GMP signaling multicellular organismal locomotion response to oxygen-glucose deprivation regulation of blood vessel diameter bone growth negative regulation of oocyte maturation meiotic cell cycle process involved in oocyte maturation cellular response to glycoprotein negative regulation of DNA biosynthetic process regulation of cAMP metabolic process regulation of cGMP metabolic process positive regulation of cGMP biosynthetic process single organism reproductive process positive regulation of vasodilation regulation of blood vessel size negative regulation of DNA metabolic process response to drug
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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