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Accelerating ScienceAnalyteGuru / Proteomics / Growing Omics Technology Challenges in the Field

Growing Omics Technology Challenges in the Field

By 07.11.2023

Recently I attended the CHI hosted BIO-IT World conference in Boston.  I was there to learn about and discuss data management solutions for the encroaching depth, breadth and size of data produced by a growing number of analytical instruments. As technology advances into detectors capable of taking wider swaths of readings at higher frequency, software is now tasked with managing terabytes of data produced in something like genomic sequencing over smaller file sizes produced by something like an IR spectrum. 

While I was minding the demonstration station, a scientist approached with a very specific and yet, identifiable omics data challenge that they were having with file management.

Looking for a data management solution

To process proteomics data with Proteome Discoverer, the lab had set up a separate computer for the task.  Files were acquired from instruments to associated acquisition PCs and those files had to be moved to the processing computer to generate results.  Then the results needed to be transferred into study summaries or removed to another location to make space on the processing computer. 

The scientist went on to describe a networking solution that they had put into place to allow file movement without external drive management. They had focused on reducing file risk and increasing the ability to share files with more people in the lab by centralizing to a network location to ensure that their users would not lose any critical information. 

Because moving large raw files took so much time, what they were asking for was some kind of help to streamline the process, compress the files, or make the transfer easier (and faster).

Offering data management solutions

I was happy to describe for the scientist how Thermo Fisher was rethinking and redesigning how software is structured from being one application that acquires, stores, secures, processes, and reports data, to a software structure with separate services and applications connected centrally. 

  • Starting with the core platform as a central file location, data from any connected acquisition application, such as Thermo Scientific Xcalibur, could directly save large omics files into the core and eliminate the need for a secondary network location altogether. 
  • Files wouldn’t need to be moved to be shared since users could access them for download through the browser interface.
  • Connected processing applications like Proteome Discoverer could be automated to utilize files directly from the source location.  
  • All of the processing activities could be completed without interference from other users accessing from other locations or additional applications running in the background allowing for multi-tasked work.
  • Lastly, having one core location for all of the data reduces data security risks with single-point access control, audit trails, backup, and archival.

Discovering the new platform

To learn more about how we are creating systems that streamline file management, economize processing power for complex files, and enable processing algorithms to work in the background to multitask getting to your omics results, read about our proteomics solution.

Crystal Welch

Crystal Welch started her industry journey in large molecule manufacturing and quality, working through several more years in process development and contributing to projects in validation, quality system initiatives, process improvements, product characterization, and regulatory submissions. After more than a decade of being a customer, she then offered consultation and support to the same departments in the field, helping others to accomplish projects in their own facilities. Now she spends her time reading regulatory policy updates, following cutting edge informatics product development, and summarizing user feedback to provide improvement suggestions with the goal to make scientists' lives easier.