Many different approaches are used in the study of programmed cell death, or apoptosis. Cell death cascades are complex and dynamic, underscoring the importance of a multi-parametric approach for accurate assessment. Understanding the mechanisms of cell death and survival can represent a critical aspect of toxicological profiling and drug discovery.
We offer a wide array of apoptosis assays for measuring multiple components on a choice of assay platforms:
Also see flow cytometry assays for apoptosis
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Caspase assays are a distinctive feature of early stage apoptosis.
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DNA fragmentation and nuclear changes characterize late apoptosis.
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Annexin V staining is used to identify intermediate apoptosis stages.
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Mitochondrial changes occur early in apoptosis.
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| Molecular Probes® Handbook BioProbes® Journal Articles | Related Products |
