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Human AmiGO2 quantitates human AmiGO2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human AmiGO2.
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ALI1, AMIGO-2, AMIGO2, DEGA
Gene ID : (Human) 347902
Gene symbol : AMIGO2
Protein Aliases : adhesion molecule with Ig-like domain 2, alivin 1, Alivin-1, AMIGO-2, AMIGO2, amphoterin induced gene 2, Amphoterin-induced protein 2, DEGA, differentially expressed in gastric adenocarcinoma, Differentially expressed in gastric adenocarcinomas, transmembrane protein AMIGO2
UniProt ID (Human) Q86SJ2
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