Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Human Cathepsin A/CTSA quantitates human Cathepsin A/CTSA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cathepsin A/CTSA.
The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease class. Cathepsins D and E comprise the aspartyle protease class. The serine protease class includes cathepsin G. Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation. Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with b-galactosidase (b-gal) and a-neuraminidase (Neu1). Cathepsin A functions to protect b-gal and Neu1 from intralysosomal proteolysis. Deficiencies in cathepsin A lead to deficiencies in b-gal and Neu1. The gene encoding human cathepsin A maps to chromosome 20q13.12. Mutations in this gene cause glactosialidosis, a lysosomal storage disorder resulting from the b-gal and Neu1 deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CTSA, GLB2, GSL, NGBE, PPCA, PPGB
Gene ID : (Human) 5476
Gene symbol : CTSA
Protein Aliases : beta-galactosidase 2, beta-galactosidase protective protein, Carboxypeptidase C, Carboxypeptidase L, carboxypeptidase Y-like kininase, carboxypeptidase-L, Cathepsin A, deamidase, lysosomal carboxypeptidase A, Lysosomal protective protein, PPCA, Protective protein cathepsin A, Protective protein for beta-galactosidase, urinary kininase
UniProt ID (Human) P10619
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support