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Invitrogen
Human DR6 ELISA Kit
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Product Specifications
Analytical sensitivity
0.04 ng/mL
Assay range
0.04-16 ng/mL
Sample type/volume
Plasma
100 µL
Supernatant
100 µL
Serum
100 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
12%
Intraassay CV
10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
-20°C
Protein name
DR6
Species (tested)
Human
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Human DR6 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human DR6 in serum, plasma, and cell culture supernatants.
Target information
DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : BM-018, CD358, DR6, TNFRSF21, UNQ437/PRO868
Gene ID : (Human) 27242
Gene symbol : TNFRSF21
Protein Aliases : CD358, Death receptor 6, Death receptor-6, MGC31965, sCD358, sDR6, soluble CD358, soluble DR6, TNFR-related death receptor 6, Tumor necrosis factor receptor superfamily member 21, tumor necrosis factor receptor superfamily, member 21
UniProt ID (Human) O75509
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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