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Human Desmocollin 2 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human Desmocollin-2 in serum, plasma, and cell culture supernatants.
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ARVD11, CDHF2, DG2, DGII/III, DSC2, DSC3
Gene ID : (Human) 1824
Gene symbol : DSC2
Protein Aliases : ARVC10, ARVD10, CDHF5, CDHF6, CMD1BB, desmoglein-2, desmoglein-3, HDGC, PVA, Cadherin family member 2, Desmocollin-2, Desmocollin-3, Desmosomal glycoprotein II, desmosomal glycoprotein II/III, Desmosomal glycoprotein III, desmosomal protein, unnamed protein product
UniProt ID (Human) Q02487
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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