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900-K316K consists of: 900-K316 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Human HRG beta-1 ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human HRG beta-1 in a sandwich ELISA format. Human HRG beta-1 ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1, NRG1-IT2, SMDF
Gene ID : (Human) 3084
Gene symbol : NRG1
Protein Aliases : acetylcholine receptor-inducing activity, glial growth factor 2, growth factor, heregulin, alpha (45kD, ERBB2 p185-activator), neu differentiation factor, neuregulin 1, NRG1, NRG1 class VII isoform alpha 2a, NRG1 class VII isoform alpha 2b, NRG1 class VII isoform alpha beta 2a, NRG1 class VII isoform alpha beta 3, NRG1 class VII isoform beta 2a, NRG1 class VII isoform beta 3, Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, sensory and motor neuron derived factor, unnamed protein product
UniProt ID (Human) Q02297
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