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Invitrogen
Human PAPPA2 ELISA Kit
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Product Specifications
Analytical sensitivity
0.23 ng/mL
Assay range
0.23-150 ng/mL
Sample type/volume
Plasma
100 µL
Supernatant
100 µL
Serum
100 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
12%
Intraassay CV
10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Sample Diluent
Wash Buffer Concentrate
Assay Buffer concentrate
Stop Solution
Substrate Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
-20°C
Protein name
PAPPA2
Species (tested)
Human
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Human PAPPA2 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human Pappalysin-2/PAPP-A2 in serum, plasma, and cell culture supernatants.
Target information
PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : PAPP-A2, PAPP-E, PAPPA2, PAPPE, PLAC3
Gene ID : (Human) 60676
Gene symbol : PAPPA2
Protein Aliases : PAPP-A2, PAPP-E, Pappalysin-2, placenta-specific 3, pregnancy-associated plasma preproprotein-A2, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1, RP4-774I24.1
UniProt ID (Human) Q9BXP8
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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