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Human PTH1R quantitates human PTH1R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PTH1R.
Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : PFE, PTH1R, PTHR, PTHR1
Gene ID : (Human) 5745
Gene symbol : PTH1R
Protein Aliases : Parathyroid hormone 1 receptor, parathyroid hormone receptor 1, Parathyroid hormone/parathyroid hormone-related peptide receptor, parathyroid hormone/parathyroid hormone-related protein receptor, PTH/PTHr receptor, PTH/PTHrP type I receptor, PTH1 receptor, seven transmembrane helix receptor
UniProt ID (Human) Q03431
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