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Human Sirtuin 3 quantitates human Sirtuin 3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Sirtuin 3.
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : SIR2L3, SIRT3
Gene ID : (Human) 23410
Gene symbol : SIRT3
Protein Aliases : hSIRT3, mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent protein deacetylase sirtuin-3, Regulatory protein SIR2 homolog 3, silent mating type information regulation 2, S.cerevisiae, homolog 3, sir2-like 3, SIR2-like protein 3, sirtuin type 3
UniProt ID (Human) Q9NTG7
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