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Human Syndecan-4 quantitates human Syndecan-4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Syndecan-4.
Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan 1 is a matrix receptor which binds to Collagens, Fibronectin and Thrombospondin. Syndecan 1 and Syndecan 3 interact with MK (midkine), a growth/differentiation factor involved in embryogenesis. Syndecan 2 is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan 4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : SDC4, SYND4
Gene ID : (Human) 6385
Gene symbol : SDC4
Protein Aliases : Amphiglycan, ryudocan amphiglycan, Ryudocan core protein, SYND4, syndecan 4 (amphiglycan, ryudocan), syndecan proteoglycan 4, Syndecan-4
UniProt ID (Human) P31431
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