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Human Transthyretin ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human TTR in serum, plasma, and cell culture supernatants.
Transthyretin (TTR), generally called prealbumin, is a plasma protein that plays an important role in physiology such as a transporter of hormone thyroxine and retinal-binding protein. After produced primarily in the liver, TTR is excreted into the plasma. TTR represents a disproportionate fraction (25%) of CSF protein, prompting the suggestion that it is either selectively transported across the blood-CSF barrier or synthesized de novo within the central nervous system. Transthyretin is a constituent found to the neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. It has been reported that more than 40 different mutations in the TTR gene associated with amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : ATTR, CTS, CTS1, HEL111, HsT2651, PALB, TBPA, TTN, TTR
Gene ID : (Human) 7276
Gene symbol : TTR
Protein Aliases : Amyloidosis I, pre-albumin, ATTR, epididymis luminal protein 111, Prealbumin, prealbumin, amyloidosis type I, TBPA, thyroxine-binding prealbumin, Transthyretin, TTR, unnamed protein product
UniProt ID (Human) P02766
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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